Estrogen-related Receptor β (ERRβ) – Renaissance Receptor or Receptor Renaissance?
نویسندگان
چکیده
منابع مشابه
Estrogen-related receptor β (ERRβ) – renaissance receptor or receptor renaissance?
Estrogen-related receptors (ERRs) are founding members of the orphan nuclear receptor (ONR) subgroup of the nuclear receptor superfamily. Twenty-seven years of study have yet to identify cognate ligands for the ERRs, though they have firmly placed ERRα and ERRγ at the intersection of cellular metabolism and oncogenesis. The pace of discovery for novel functions of ERRβ, however, has until recen...
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Estrogen-related receptor (ERR) is a member of the nuclear receptor superfamily that has strong homology with estrogen receptor (ER) α. ERR has three subtypes (α, β, and γ) expressed in estrogen-sensitive organs, including ovary, breast, and brain. No endogenous ligands of ERRs have been identified, but these receptors share a common DNA element with ERα and control estrogen-mediated gene trans...
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ژورنال
عنوان ژورنال: Nuclear Receptor Signaling
سال: 2016
ISSN: 1550-7629,1550-7629
DOI: 10.1621/nrs.14002